PMA and PMMA: Mental effects

Last modified: Saturday, 20. June 2009 - 2:54 pm

PMA and ecstasy are pharmacologically similar, producing their effects through very similar or identical mechanisms. While little research has been done on the Mental effects of PMA, they are thought to be very similar to those of ecstasy. Studies done by the National Institute of Mental Health (NIMH) in the year 2001 assessed the effects of ecstasy on the human brain. It was discovered that recreational ecstasy use damages the nerve cells, or neurons, that employ the neurotransmitters serotonin, dopamine, and acetylcholine to send information to other neurons of the brain. The use of ecstasy causes an increase in brain serotonin concentrations that deliver the “desirable” effects of ecstasy on the user. The same increase in brain serotonin concentrations also permanently damages the neurons making serotonin. The damage of these neurons eventually leads to a decrease in the level of serotonin present in the brain, resulting in many long-term complications.
Ecstasy or PMA users risk enduring brain damage similar to that found in many neurological diseases. Neuron damage may cause undesirable Mental effects including depression, anxiety, loss of memory, learning deficits, difficulty solving simple problems, lack of self-control, sleep disorders, sexual dysfunction, and neuropsychiatric disorders. When a toxin such as ecstasy or PMA is ingested, neuron death occurs immediately upon exposure to the drug. However, the functional aspects of the brain damage may not show up until months or years later. Panic attacks may occur even after months of abstinence from ecstasy usage. Also, recurring paranoia, hallucinations, flashbacks, and psychotic episodes have been caused by ecstasy usage long after the actual time frame in which ecstasy was consumed. Chronic users of PMA or ecstasy may develop a psychological dependence to these drugs.

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