Meperidine: Therapeutic use
Last modified: Sunday, 31. May 2009 - 5:17 pm
Meperidine is used for the treatment of moderate-to-severe pain, most commonly following surgery. It is sometimes given as an adjunct to anesthesia just before and during surgery. Meperidine also remains one of the more frequently used opioid analgesics in obstetric departments for severe pain during labor and delivery. Meperidine may be preferred over morphine after surgery because it produces less nausea and constipation in most people.
Meperidine is generally not recommended for use in infants and small children. Likewise, the elderly may have underlying medical conditions that present special risks with meperidine use.
Meperidine is occasionally used in outpatients for the treatment of acute pain, especially if other opioids prove ineffective. Its use for chronic pain is less accepted. Meperidine is eliminated from the body more quickly than other opioids, which means it must be taken more frequently, and its analgesic effects fluctuate more rapidly.